Table 3.
Kaplan-Meier overall survival analysis for patients with brain metastases at diagnosis treated with whole brain radiation therapy (WBRT) or stereotactic radiosurgery (SRS)
| Median survival, months (95% CI) | 6-mo survival, % (95% CI) | 36-mo survival, % (95% CI) | |
|---|---|---|---|
| SRS (n = 8715) | 11.7 (11.3-12.0) | 72.2 (71.2-73.0) | 18.9 (18.0-19.8) |
| WBRT (n = 20,611) | 5.7 (5.6-5.9) | 48.5 (47.8-49.2) | 6.4 (6.0-6.8) |
| ShWBRT (n = 854) | 1.9 (1.8-2.2) | 16.9 (14.5-19.7) | 2.7 (1.7-4.3) |
| StWBRT (n = 18,935) | 5.9 (5.8-6.0) | 49.4 (48.7-50.1) | 6.4 (6.1-6.9) |
| ExWBRT (n = 822) | 8.3 (7.4-9.3) | 59.8 (56.5-63.2) | 9.3 (7.5-11.7) |
Abbreviations: CI = confidence interval; ExWBRT = extended dose-fractionations; ShWBRT = short dose-fractionations; SRS = stereotactic radiosurgery; StWBRT = standard dose-fractionations.