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. 2020 Jan 31;10:1625. doi: 10.3389/fphys.2019.01625

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Copyright © 2020 Chen, Liu, Wang, Liu, Fan, Wang, Xu, Zhang, Gyawali, Li, Ling and Yin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The transcript levels of RAS components (ACE/ACE2/ATIR) in the hypothalamus determined by real-time RT-PCR (A–C) and concentration of Ang-(1-7) in the hypothalamus measured via ELISA (D). The different lowercase letters show significant differences of the variable among groups (p < 0.05), whereas the same lowercase letters show no statistical differences (p > 0.05). RAS, renin–angiotensin system; ACE, angiotensin-converting enzyme; AT1R, AngII type 1 receptor; Ang-(1-7), angiotensin-(1-7).