Table 1.
Descriptive characteristics of the ROS/MAP participants (N = 300).
| Characteristic | N | Percentage | |
|---|---|---|---|
| Sex (female) | 183 | 61.0 | |
| Diagnosis rendered at death | |||
| Normal cognition | 167 | 55.7 | |
| Mild cognitive impairment | 133 | 44.3 | |
| Study | |||
| ROS | 164 | 54.7 | |
| MAP | 136 | 45.3 | |
| Mean [SD] | Median | Range | |
| Age at enrollment | 65.3 [7.2] | 80.4 | [65 to 98] |
| Age at death | 86.9 [6.6] | 86.9 | [67 to 104] |
| Education | 16.5 [3.5] | 16.0 | [5 to 26] |
| Depression score (average over all follow-up years)a | 1.3 [1.3] | 0.9 | [0 to 7] |
| Rate of cognitive declineb | 0.04 [0.04] | 0.04 | [−0.10 to 0.14] |
| Number of follow-up years | 6.9 [3.9] | 6.0 | [1 to 17] |
| Postmortem interval (PMI) | 7.3 [5.0] | 5.9 | [1 to 32.6] |
| RNA integrity number (RIN) | 7.2 [1.0] | 7.4 | [5 to 9.9] |
| Global AD pathology | 0.5 [0.5] | 0.3 | [0 to 2.3] |
aCES-D has a possible score of 0 to 10 with the higher score, the more depressive symptoms
bRate of cognitive decline refers to the slope of a person's cognitive trajectory over the follow-up years. Hence, the more negative the slope, the faster the decline