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. 2020 Jan 31;10:31. doi: 10.3389/fonc.2020.00031

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Copyright © 2020 Sun, Chen, Sun, Wang, Huang, Gao, Liang, Liu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic analysis after knockdown BAG2. (A) Efficiency verification of shRNA for BAG2 knockdown in the HGC27 cell line (** P < 0.01); (B) Volcanic map of DEPs showed 97 up-regulated and 95 down-regulated (when the difference multiple was more than 1.2 times or <1/1.2 times. The p-value was <0.05 by t-test, which was regarded as DEPs); (C) iTRAQ proteomic analysis of biological processes (BP), cell component (CC) and molecular function (MF) in which BAG2 may be involved; (D) Clustering map of partial BAG2-related DEPs with statistical differences.