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Effects of BAG2 knockdown on AKT/mTOR pathway, ERK pathway, and EMT process. (A) BAG2 knockdown significantly inhibits the expression of AKT, mTOR, p38, ERK1/2; (B) Immunoprecipitation result showed that BAG2 could bind to ERK1/2; (C) BAG2 knockdown significantly up-regulated E-cadherin and inhibited the expression of N-cadherin, MMP9, Vimentin and Snail, which were related to EMT process. *P < 0.05; **P < 0.01.
