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. 2019 Nov 27;47(3):695–712. doi: 10.1007/s00259-019-04583-2

Table 5.

Dosimetric calculations of the salivary glands after 177Lu-PSMA-617 therapy (SUVmax, volume)

Parotid glands Submandibular glands
Absorbed dose Baseline After 2–4 cycles Absorbed dose Baseline After 2–4 cycles
Patient Therapy cycles Accumulated activity (GBq) D/Aa(Gy/GBq) Dtotb (Gy) SUVmax Volume (ml) SUVmax Volume (ml) D/A1(Gy/GBq) Dtot2 (Gy) SUVmax Volume (ml) SUVmax Volume (ml)
1 3 17.74 0.39 6.92 26.00 27.00 15.45 21.40 0.46 8.16 19.65 8.65 11.45 8.00
2 4 19.34 0.60 11.60 14.40 29.23 10.55 22.25 0.46 8.90 16.80 7.57 11.35 6.10
3 4 18.63 0.25 4.66 9.35 24.65 8.45 21.00 0.66 12.30 12.45 9.05 13.85 6.85
4 3 16.30 0.45 7.34 10.25 18.75 10.20 14.95 0.22 3.59 10.35 9.40 10.65 9.10
5 4 17.88 0.75 13.41 7.85 25.75 10.05 19.80 0.65 11.62 8.35 7.45 10.25 6.15
6 4 18.12 0.85 15.40 17.80 22.35 10.35 21.50 0.63 11.42 23.15 9.85 14.20 8.20
7 3 18.83 0.50 9.42 14.95 18.90 16.95 15.80 0.58 10.92 17.50 9.30 18.25 8.05
8 2 12.70 1.04 13.21 7.50 34.00 7.00 26.00 0.44 5.59 9.05 7.30 7.45 6.10
9 3 18.59 0.42 7.81 8.05 25.70 8.75 17.30 / / 7.00 7.35 4.75 7.25
10 4 + 2 24.30 0.36 8.75 7.80 23.50 18.70 29.00 0.38 9.23 9.40 10.35 17.50 11.95
11 4 + 2 25.61 0.37 9.47 18.50 20.39 15.65 21.95 0.41 10.50 16.60 8.00 13.40 7.62
12 2 12.79 0.90 11.51 17.10 18.53 9.35 22.34 0.70 8.95 17.10 11.15 7.70 12.51
13 4 25.32 0.44 11.14 26.45 21.86 11.10 13.35 0.45 11.39 28.40 9.49 13.30 6.16
14 4 24.90 0.85 21.16 16.20 56.10 / / 0.30 7.47 19.30 10.16 / /
15 3 18.29 0.72 13.16 10.80 16.79 8.65 18.62 0.70 12.80 15.75 7.25 14.75 5.68
16 4 23.34 0.26 4.70 13.20 20.24 / / 0.24 4.34 13.65 7.53 / /
17 4 24.93 0.54 / 14.70 15.64 19.35 24.15 0.16 0.97 7.75 1.85 8.22 6.65
18 3 18.10 0.80 14.48 13.10 14.13 9.35 8.16 0.80 14.48 12.55 8.36 6.20 6.35
19 4 24.40 0.36 6.76 13.85 18.82 8.55 13.74 0.52 9.77 18.65 8.31 8.30 5.77
20 4 24.80 0.58 14.38 24.30 14.35 16.95 12.52 0.30 7.44 22.90 13.02 18.70 9.10
21 2 10.76 0.50 5.38 10.90 21.66 16.60 22.05 0.37 3.98 13.00 8.31 16.15 8.50
22 4 23.80 0.50 11.90 16.50 30.66 10.85 24.16 0.19 4.52 20.75 8.75 14.15 7.82
23 4 24.61 0.30 7.38 17.26 20.70 11.28 20.10 0.52 12.79 24.87 8.13 14.58 7.68
24 4 25.27 0.23 5.81 / / / / 0.28 7.07 / / / /
25 4 24.40 / / 15.25 21.66 / / / / 20.75 4.88 / /
26 4 25.34 0.65 16.47 10.15 17.26 10.75 10.82 0.65 16.47 5.90 4.64 10.90 5.43
27 3 19.00 0.44 8.36 13.15 29.19 / / 0.44 8.36 18.35 10.17 / /
28 4 + 1 25.00 0.81 20.25 15.45 28.94 22.00 26.06 0.35 8.75 19.85 11.44 19.85 10.56
29 3 16.04 0.60 9.62 23.70 16.77 15.90 14.03 0.50 8.02 22.15 6.50 19.00 4.93
30 4 + 1 25.54 0.48 12.29 29.69 17.18 12.49 12.91 0.34 8.68 33.93 8.66 19.67 7.62
31 4 23.74 0.40 9.49 23.20 22.09 9.35 21.21 0.65 15.43 28.41 8.27 21.21 9.66
32 4 21.49 0.22 4.72 26.37 13.97 8.20 11.63 0.33 7.09 32.75 5.91 8.40 5.57
Mean 20.93 0.53 10.56 15.93 22.80 12.33 18.77 0.46 9.03 17.65 8.29 13.12 7.61
SD 4.33 0.22 4.33 6.23 8.07 4.07 5.35 0.17 3.61 7.34 2.15 4.62 1.93
Min 10.76 0.22 4.66 7.50 13.97 7.00 8.16 0.16 0.97 5.90 1.85 4.75 4.93
Max 25.61 1.04 21.16 29.69 56.10 22.00 29.00 0.80 16.47 33.93 13.02 21.21 12.51
Max/min 2.38 4.73 4.54 3.96 4.02 3.14 3.55 5.00 16.98 5.75 7.04 4.47 2.54

aabsorbed dose per unit administered activity

btotal cumulative dose