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. 2019 Dec 21;412(4):811–818. doi: 10.1007/s00216-019-02319-7

Table 1.

Figures of merits of the most relevant analytical methods for HIV-1 p24 detection

HIV-1 p24 limit of detection Selectivity Dynamic range Label Time to result
ELISA [23] 400 nM High 4 orders of magnitude Label-needing Long
Nanoparticle-based bio-barcode [23] 4 nM High 6 orders of magnitude Label-needing Long
Immuno-polymerase chain reaction [25] 100 fM High 3 orders of magnitude Label-needing Short (few hours)
Multi-walled carbon nanotube electrochemical sensor [27] 3 fM High 4 orders of magnitude Label needing Short (few hours)
SiMoT 30 zM (2±1 molecules in 100 mL) High 2 orders of magnitude Label-free Short (few hours)