Table 3.
Baseline characteristics and drug prescription at discharge in MINOCA sub-groups.
| Non-obstructive CAD Patients (N = 22) |
Normal coronary arteries Patients (N = 66) |
P-value | |
|---|---|---|---|
| Age years, mean (SD) | 69.32 (10.45) | 66.63 (14.17) | 0.59 |
| Gender female, n (%) | 13 (59.1) | 42 (63.6) | 0.70 |
| BMI kg/m2, mean (SD) | 25.68 (4.73) | 25.65 (4.05) | 0.98 |
|
Cardiovascular risk factors Current/past smoking, n (%) |
12 (54.5) | 33 (50.8) | 0.76 |
| Hypertension, n (%) | 14 (63.6) | 46 (70.8) | 0.53 |
| Dyslipidemia, n (%) | 15 (68.2) | 46 (70.8) | 0.82 |
| Type-2 diabetes, n (%) | 3 (13.6) | 8 (12.3) | 0.87 |
|
Medical history Previous MI, n (%) |
1 (5.3) | 10 (19.2) | 0.15 |
| Previous stroke, n (%) | 2 (9.1) | 6 (9.1) | 1.0 |
| Atrial fibrillation, n (%) | 2 (9.1) | 4 (6.2) | 0.64 |
|
Admission diagnosis STEMI, n (%) |
4 (19.0) | 8 (13.1) | 0.51 |
|
Laboratory parameters GFR CKD-EPI ml/min, mean (SD) |
72.62 (24.02) | 73.71 (23.46) | 0.76 |
| Hemoglobin g/dl, mean (SD) | 13.33 (1.94) | 13.51 (1.75) | 0.73 |
|
Echocardiogram LVEDV ml, mean (SD) |
87.67 (25.24) | 87.46 (25.67) | 0.97 |
| % EF, mean (SD) | 57.78 (13.63) | 57.27 (7.92) | 0.51 |
|
Medical Therapy at discharge Single antiplatelet, n (%) |
20 (90.9) | 57 (86.4) | 0.58 |
| ASA, n (%) | 19 (86.4) | 56 (84.8) | 0.86 |
| P2Y12 inhibitor, n (%) | 17 (77.3) | 37 (56.1) | 0.07 |
| Dual antiplatelet therapy, n (%) | 16 (72.7) | 34 (51.5) | 0.08 |
| Beta-blockers, n (%) | 20 (90.9) | 57 (86.4) | 0.58 |
| RAAS inhibitor, n (%) | 14 (63.6) | 49 (74.2) | 0.34 |
| Statins, n (%) | 18 (81.8) | 48 (72.7) | 0.39 |
BMI, body mass index; MI, myocardial infarction; STEMI, ST elevation myocardial infarction; NSTEMI, non ST elevation myocardial infarction; GFR, glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CRP, C-reactive Protein; LVEDd, left ventricular end diastolic diameter; LVEDV, left ventricular end diastolic volume; EF, ejection fraction; RAAS, renin-angiotensin-aldosterone system; SD, Standard deviation.
Chi-square test for categorical variables; Student's t-test for normally distributed continuous variables and Mann-Whitney test and for non-normally distributed continuous variables.