Table 1A.
Characteristic of included studies.
| References | Country | Male/female | Demographic of subjects | Complete blood count | Iron metabolism marker |
Positive results (p < 0.05) |
|---|---|---|---|---|---|---|
| Hutter et al. (2001) | Netherlands | TG: 19/20 CG: 24/18 | Severe CPD | HB, RBC, HCT, MCV, MCH, MCHC |
NA | HB, RBC, HCT, |
| Naik et al. (2010) | India | All male | 30–60 years ≥20 teeth BMI: 18.5–25 |
HB,RBC, HCT, MCV, MCHC, ESR |
NA | HB,RBC, HCT, MCV, MCHC, ESR |
| Gokhale et al. (2010) | India | All male | 25–50 years | HB, RBC, HCT MCV, MCH, MCHC | NA | RBC, HCT, HB |
| Prakash et al. (2012) | India | TG: 51/39 CG: 27/23 |
35–65 years | HB, HCT MCV, MCH, MCHC, ESR | sFe, sFerritin | NA |
| Patel et al. (2014) | India | All male | 20–50 years | HB, RBC, HCT MCV, MCH, MCHC | NA | HB, RBC, HCT, MCV MCH, MCHC |
| Chakraborty et al. (2014) | India | TG: 9/11 CG: 12/10 | TG: 33.13 ± 6.38 (24–42 years) CG: 36.18 ± 5.15 (24–42 years) |
HB | sFerritin | HB, ferritin |
| Khan et al. (2015) | India | All male | ≤ 55 years | HB, RBC, HCT, MCV, MCH, MCHC |
NA | HB, RBC, HCT, MCV, MCH, MCHC |
| Latha et al. (2015) | India | TG: 7/7 CG: 5/9 |
40–50 years | HB, RBC, HCT MCV, MCH, MCHC, ESR, | sFerritin | NA |
| Anumolu et al. (2016) | India | TG: 33/17 CG: 27/23 |
20–55 years | HB, RBC, HCT MCV, MCH, MCHC, ESR |
NA | HB, RBC, |
| Carvalho et al. (2016) | Brazil | NA | NA | HB, MCV, MCH, HCT | sFe, sFerritin Transferrin Hepcidin |
NA |
| Kolte et al. (2014) | India | TG: 47/53 CG: 42/58 |
30–60 years | HB, MCV, MCH | NA | RBC MCHC |
| Nibal et al. (2019) | UK | TG: 50/71 CG: 104/121 |
TG: 45.12 ± 10.04 CG: 37.65 ± 11.52 |
HB, RBC, HCT MCV, MCH, MCHC | NA | NA |
| Shirmohamadi et al. (2016) | Iran | TG: 11/9 CG: 9/11 | TG: 42.13 ± 8.36 (28–56 years) CG: 33.1 ± 4.41 (25–42 years) |
NA | Transferrin | Transferrin |
| Thomas et al. (2013) | India | NA | 35–60 years | NA | sFe | sFe |
| Craig et al. (2003) | India | NA | TG: 38.7 ± 1.3 CG: 29.9 ± 1.1 |
NA | sFe | |
| Guo et al. (2018) | China | TG: 9/11 CG: 14/8 |
CG: 52.45 ± 10.01 TG: 58.09 ± 9.97 |
NA | Hepcidin | Hepcidin |
CPD, chronic periodontal disease; CG, control group; EC, erythrocyte count; ESR, erythrocyte sedimentation rate; HCT, hematocrit; HB, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; RBC, red blood cell count; RDW, red cell distribution width; TG, test group; NA, not available. Values are given as mean ± SD unless the variable is not normally distributed (indicated by the superscript letter, in which case (median, range) are also given.