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. 2020 Jan 31;10:1620. doi: 10.3389/fphys.2019.01620

Table 1B.

Characteristic of included studies.

References Case/control Case/control ratio estimation Case/control matching Criteria of CPD Criteria of Control Temporal association NOS
Hutter et al. (2001) 39/42 NA Yes BL ≥ 50% (≥7 teeth) CEJ to alveolar bone crest
<2 mm
In parallel 6
Naik et al. (2010) 15/15 NA Yes CAL: 30% sites ≥ 5 mm, or most sites ≥ 6 mm CAL: 0% sites In parallel 7
Gokhale et al. (2010) 30/30 NA NA PD ≥ 6 mm (30% sites)
BL > 50%
PD <3 mm In parallel 5
Prakash et al. (2012) 90/50 NA Yes CAL ≥ 2 mm PD <3 mm
CAL: 0% sites; without BL
In parallel 6
Patel et al. (2014) 50/50 NA Yes PD ≥ 2 mm and AL ≥ 2 mm (30% sites) PD <3 mm
CAL: 0% sites
In parallel 6
Chakraborty et al. (2014) 20/22 A significant difference in BOP% with 80%
power and two-sided 0.05 level of significance
NA CAL ≥ 4 mm, PD ≥ 5 mm (≥2 interproximal sites) In parallel 6
Khan et al. (2015) 20/20 NA Yes PD ≥ 4 mm and CAL ≥ 5 mm Clinically healthy gingival In parallel 6
Latha et al. (2015) 14/14 NA NA PD ≥ 4 mm and CAL ≥ 1 mm PD <3 mm
CAL: 0% sites
In parallel 6
Anumolu et al. (2016) 50/50 NA NA PD ≥ 5 mm (30% sites) and CAL ≥ 2 mm GI: 0–1 In parallel 6
Carvalho et al. (2016) 33/30 NA NA PD ≥ 5 mm and AL ≥ 6 mm Absence of periodontal infection In parallel 6
Kolte et al. (2014) 100/100 NA NA PD ≥ 5 mm PD ≤ 3 mm In parallel 6
Nibal et al. (2019) 121/225 NA NA PD and CAL ≥ 5 mm PD and CAL <5 mm (≥20 teeth) In parallel 6
Shirmohamadi et al. (2016) 20/20 α = 0.05 and a statistical power of 80% NA CAL ≥ 4 mm, PD ≥ 5 mm (≥2 interproximal sites) PD <3 mm
CAL: 0% sites
In parallel 6
Thomas et al. (2013) 50/50 NA NA CAL ≥ 4 mm (30% sites) PD ≤ 3 mm
GI ≤ 2 (≥20 teeth)
In parallel 6
Craig et al. (2003) 44/25 NA Yes CAL > 3 mm, PD > 3 mm (≥4 sites) CAL <3 mm (≥24 teeth) In parallel 6
Guo et al. (2018) 22/22 NA NA BL ≥ 30%, CAL ≥ 5 mm, PD ≥ 5 mm Clinically healthy gingival In parallel 6

BL, alveolar bone loss; CAL, clinical attachment level; CEJ, cemento-enamel junction; CPD, chronic periodontal disease; CG, control group; GI, gingival index; NA, not available; PD, probing depth.