Table 2.
Functions of potential target genes based on KEGG pathway analysis.
| No | Term | P Value | Genes |
|---|---|---|---|
| 1 | hsa04621: NOD-like receptor signaling pathway | 1.24E-11 | MAPK1, CARD8, IL6, TNF, CCL2, RELA, CXCL2, IL1B, NFKB1, CASP1, NLRP3 |
| 2 | hsa04620: Toll-like receptor signaling pathway | 7.54E-06 | MAPK1, IL6, TNF, RELA, IL1B, NFKB1, TLR4, CD14 |
| 3 | hsa04060: Cytokine-cytokine receptor interaction | 5.65E-04 | IL4, CSF2, IL6, TNF, CCL2, CCL20, CXCL2, IL1B, TGFB1 |
| 4 | hsa04623: Cytosolic DNA-sensing pathway | 6.88E-04 | IL6, RELA, IL1B, NFKB1, CASP1 |
| 5 | hsa04660: T cell receptor signaling pathway | 0.0011312 | IL4, CSF2, MAPK1, TNF, RELA, NFKB1 |
| 6 | hsa04664: Fc epsilon RI signaling pathway | 0.0025462 | IL4, CSF2, MAPK1, TNF, SYK |
| 7 | hsa04062: Chemokine signaling pathway | 0.011938 | MAPK1, CCL2, CCL20, RELA, CXCL2, NFKB1 |
| 8 | hsa04010: MAPK signaling pathway | 0.0132372 | MAPK1, TNF, RELA, IL1B, NFKB1, CD14, TGFB1 |
| 9 | hsa04920: Adipocytokine signaling pathway | 0.0132749 | PPARA, TNF, RELA, NFKB1 |
| 10 | hsa04662: B cell receptor signaling pathway | 0.0179629 | MAPK1, RELA, NFKB1, SYK |
| 11 | hsa04210: Apoptosis | 0.0265251 | TNF, RELA, IL1B, NFKB1 |