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. 2020 Jan 31;10:1792. doi: 10.3389/fpls.2019.01792

Table 1.

Root metabolites affecting nematode movement.

Plant species/ synthetic chemicals Root metabolites Assay concentrations Test system Nematodes affected Effect Reference
1Tomato Solanum lycopersicum Methyl salicylate 40, 80, 160 ng/µl dissolved in hexane, hexane as negative control Olfactory assay with sterilized sand Meloidogyne incognita Attractant (Murungi et al., 2018)
1Spinach Spinacia oleracea 2-isopropyl-3-methoxypyrazine, tridecane 40, 80, 160 ng/µl dissolved in hexane, hexane as negative control Olfactory assay with sterilized sand M. incognita Attractant (Murungi et al., 2018)
1Pepper Capsicum annuum Methyl salicylate, α-pinene, limonene and tridecane 20, 40, 80 ng/µl µl dissolved in hexane, hexane as negative control Olfactory assay with sand M. incognita Attractant (Kihika et al., 2017)
3Synthetic chemicals Isoamyl alcohol, 1-butanol, and 2-butanone Dissolved in sterile ethanol (0.05% v/v) final concentration NA, water as negative control In vitro assay M. incognita Attractant (Shivakumara et al., 2018)
3Synthetic chemicals Salicylic acid 20, 50, 100, 200 µg/ml; controls consisted of the compound solvent (0.5% DMSO, 2.5 mM NaOH or distilled water), 1% acetic acid as a repellent and 0.5 M CaCl2 as an attractant control. In vitro assay M. incognita Attractant (Wuyts et al., 2006)
1Tomato S. lycopersicum Zeatin 4, 15.6, 62.3, 250, 1000 ng/μl dissolved in 2% DMSO; 2% DMSO as negative control and 100 ng/μlmethyl salicylate as positive control Sand assay M. incognita Attractant (Kirwa et al., 2018)
3Synthetic chemicals Dopamine 20, 50, 100, 200 µg/ml; controls consisted of the compound solvent (0.5% DMSO, 2.5 mM NaOH or distilled water), 1% acetic acid as a repellent and 0.5 M CaCl2 as an attractant control. In vitro assay Radophulus similis Attractant (Wuyts et al., 2006)
1Tomato S. lycopersicum L-ascorbyl 2, 6-dipalmitate; 2, 6-Di-tert-butyl-p-cresol; dibutyl phthalate and dimethyl phthalate 0.5mM, 1.1mM, 2.2mM dissolved in 1% ethanol, 1% ethanol as control In vitro assay M. incognita Dimethyl phthalate repellent, all four compounds nematicidal (Yang et al., 2016)
1Castor Ricinus communis Palmitic acid and linoleic acid 0.5,1, 2, 4 mM dissolved in methanol, methanol as control In vitro assay M. incognita Repellent (Dong et al., 2018)
1Tomato S. lycopersicum Quercetin 4, 15.6, 62.3, 250, 1000 ng/μl dissolved in 2% DMSO; 2% DMSO as negative control, 100 ng/μl methyl salicylate as positive control Sand assay M. incognita Low concentration act as attractant and higher concentration as repellent (Kirwa et al., 2018)
3Synthetic chemicals 1-octanol Dissolved in sterile ethanol (0.05% v/v), final concentration NA, water as negative control In vitro assay M. incognita Repellent (Shivakumara et al., 2018)
2Marigold Tagetes patula, 2Pepper Capsicum annuum, and 2Soybean Glycine max Root exudate compounds Extract doses in bioassays expressed as mg of tip section (mg eq) volume−1, 1 to10 mg equivalent dispenser-1; double distilled water as control In vitro assay M. incognita and Heterodera glycine Repellent to root knot nematode and attractant to cyst nematode (Wang et al., 2018)
2Pea Pisum sativum, 2Snap bean Phaseolus vulgaris, and 2Alfalfa Medicago sativa cv. Thor, cv. Moapa 69, cv. Lahonton Root tip exudates Border cells, root tip exudates, and border cells + root tip exudates with water as control In vitro assay M. incognita Repellent to J2s; induced quiescence response, > 80% of the nematodes lost motility (Zhao et al., 2000)
1Tomato S. lycopersicum and 1Rice Oryza sativa Small lipophilic molecules Dissolved in 0.01% ethanol, final concentration NA, 0.01% ethanol and distilled water as control In vitro assay M. incognita and Meloidogyne graminicola Repellent (Dutta et al., 2012)
3Synthetic chemicals p-coumaric acid, caffeic acid, ferulic acid, kaempferol, quercetin, myricetin 20, 50, 100, 200 µg/ml; controls consisted of the compound solvent (0.5% DMSO, 2.5 mM NaOH or distilled water), 1% acetic acid as a repellent and 0.5 M CaCl2 as an attractant control M. incognita Repellent (Wuyts et al., 2006)
3Synthetic chemicals Protocatechuic acid, umbelliferone, caffeic acid, ferulic acid, luteolin, daidzein, genistein, kaempferol, quercetin, myricetin 20, 50, 100, 200 µg/ml; controls consisted of the compound solvent (0.5% DMSO, 2.5 mM NaOH or distilled water), 1% acetic acid as a repellent and 0.5 M CaCl2 as an attractant control R. similis Repellent and nematicidal (Wuyts et al., 2006)
2Potato Solanum tuberosum Unknown volatile metabolites in root exudates NA Bioassay in sand Globodera pallida Attractants (Farnier et al., 2012)
3Synthetic chemicals Trans-cinnamic acid; p-coumaric acid Trans-cinnamic acid 270 µM; p-coumaric acid 240 µM, water as control In vitro assay M. incognita Repellent (Fleming et al., 2017)
3Synthetic chemicals Salicylic acid, ethephon, vanillic acid, gibberellic acid, indole-3-acetic acid, 6-dimethylallylamino purine, mannitol, arginine and lysine Salicylic acid 100 µM; ethephon 1, 10, 50 µM; vanillic acid 240 µM; gibberellic acid 115 µM; indole-3-acetic acid 230 µM; 6-dimethylallylamino purine 200 µM; mannitol 5 mM; arginine 5 mM; and lysine, 5 mM; water as control In vitro assay M. incognita Attractants (Fleming et al., 2017)
3Synthetic chemicals Salicylic acid, methyl jasmonate, ethephon, indole-3-acetic acid, mannitol Salicylic acid 100 µM; methyl jasmonate 100 µM; ethephon 50 µM; indole-3-acetic acid 230 µM; mannitol 5 mM, water as control In vitro assay G. pallida Attractants (Fleming et al., 2017)
1Crown daisyGlebionis coronaria Lauric acid 0.5, 1.0, 2.0, and 4.0mM dissolved in methanol, methanol as control In vitro assay M. incognita Lauric acid (0.5, 1.0, 2.0 mM) acts as attractant and lethal trap and also act as repellent (4mM) (Dong et al., 2014)
2Soybean Glycine max and 2Arabidopsis Arabidopsis thaliana Metabolites of ethylene pathway NA In vitro assay Heterodera glycines Ethylene (ET)-synthesis inhibitor and ET-insensitive mutations attractant to cyst nematode (Hu et al., 2017)
2Thale cress Arabidopsis thaliana Metabolites of ethylene pathway NA In vitro assay Heterodera schachtii Ethylene treated Arabidopsis more attractive to nematodes (Kammerhofer et al., 2015)
2Thale cress Arabidopsis thaliana and 2Tomato S. lycopersicum Metabolites of ethylene pathway NA In vitro assay Meloidogyne hapla Ethylene (ET)-synthesis inhibitor and ET-insensitive mutations attractant while ET-overproducing mutants less attractive (Fudali et al., 2012)
2Tomato S. lycopersicum and 2barrel clover Medicago truncatula Metabolites of ethylene pathway NA In vitro assay M. hapla, Meloidogyne javanica, and M. incognita Mutants defective in ethylene signaling of both hosts were found to be more attractive compared to wild type (Čepulyte et al., 2018)

1study on effect of both plant and specific metabolites detected in root exudates of the plant, 2study on effect of plant, 3study on effect of synthetic compound on nematodes, NA indicate not applicable.