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. 2020 Jan 31;11:86. doi: 10.3389/fimmu.2020.00086

Table 1.

Clinical characteristics of the study groups.

Healthy/gingivitis (n = 133) Periodontitis
stage I/II
(n = 95)
Periodontitis
stage III/IV
(n = 108)
p-value*
Age (years) 45.9 (±19.1) 47.7 (±15.1) 61.5 (±13.3)a,b <0.001
Males, n (%) 55 (41.4) 50 (52.6) 61 (56.5) 0.041
Females, n (%) 78 (58.6) 45 (47.4) 47 (43.5)
Smokers, n (%) 15 (11.3) 12 (12.6) 17 (15.7) 0.596
N° teeth 25.5 (±4.2) 26.3 (±2.6) 24.0 (±4.0)a,b <0.001
Plaque index (%) 18.9 (±26.0) 17.1 (±16.8) 22.4 (±23.1)a 0.011
BOP (%) 5.5 (±13.5) 10.4 (±8.1)a 14.3 (±14.6)a <0.001
PPD 4–5 mm (n) 7.0 (±6.7) 19.2 (±18.8) <0.001
PPD ≥ 6 mm (n) 1.3 (±2.2)

BOP, bleeding on probing; PPD, probing pocket depth.

*

Kruskal–Wallis/Mann–Whitney test or Chi-square test.

a

p < 0.05 in comparison to healthy/gingivitis group.

b

p < 0.05 in comparison to periodontitis stage I/II group.