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. 2020 Feb 6;10:2043. doi: 10.1038/s41598-020-58970-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Survival analysis and methylation status of cases with either a high or low SOX11 mRNA expression. (a) Kaplan–Meier survival curves and p-values of Log-rank test for EFS in patients with a low or high expression of SOX11 and in patients with a low or high methylation of the SOX11 gene locus. (b) CpG sites at the SOX11 locus in chromosome 2³⁵. (c) DNA methylation at the SOX11 gene locus among patients with either a low or high expression of SOX11. (d) Effect of decitabine treatment on SOX11 mRNA expression in the KOPN-8 cell line. Reproduced with permission⁶⁶.