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. 2020 Feb 6;11(2):96. doi: 10.1038/s41419-020-2296-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a CRAMP levels in mouse heart and MHECs after injection with AAV9-shCRAMP for 1, 4, or 8 weeks. b HW/BW, HW/TL in mice undergoing 8 weeks of AB injected with AAV9-shCRAMP (n = 10). c LW/BW, LW/TL in mice (n = 10). d H&E staining (n = 6) and cell cross-sectional area (n > 200 cells/group) in mice. e Fetal gene transcription level (n = 6). f PSR staining (n = 6) and LV collagen volume in mice. g Fibrosis gene transcription level (n = 6). h Echocardiography analysis (n = 8). *P < 0.05 vs. CON-sham; ^#P < 0.05 vs. CON-AB.