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. 2020 Feb 6;11(2):96. doi: 10.1038/s41419-020-2296-4

Fig. 4. CRAMP affected inflammation and oxidative stress in the heart.

Fig. 4

a SOD, Gpx, DHE and NADPH oxidase activity in mouse heart 8 weeks after AB surgery and treatment with CRAMP (n = 6). b NOX2 and NOX4 level in heart tissue treated with CRAMP (n = 6). c TNFα, IL-1, IL-6 levels in mouse heart 8 weeks after AB surgery and treatment with CRAMP (n = 6). *P < 0.05 vs. vehicle-sham; #P < 0.05 vs. vehicle-AB. d SOD, Gpx, DHE, and NADPH oxidase activity in mouse heart 8 weeks after AB surgery and injection with AAV9-shCRAMP (n = 6). e NOX2 and NOX4 level in heart tissue injected with AAV9-shCRAMP (n = 6). f TNFα, IL-1, IL-6 levels in mouse heart 8 weeks after AB surgery and injection with AAV9-shCRAMP (n = 6). *P < 0.05 vs. CON-sham; #P < 0.05 vs. CON-AB.