Table 1.
Data categories and measures ALS = amyotrophic lateral sclerosis; ALSFRS-R = amyotrophic lateral sclerosis functional rating scale-revised; PLS = Primary lateral sclerosis; CA = Cornu Ammonis; GC-DG = granule cell layer of the dentate gyrus; HATA = hippocampus-amygdala transition area, Lt = Left, Rt = Right.
| Data categories | Specific measures |
|---|---|
| Demographic variables | Age (year) |
| Gender (Male/Female) | |
| Years of education (years) | |
| Handedness (Rt/Lt) | |
| Clinical data for ALS and PLS | Symptom duration (months) |
| ALSFRS-R (max 48) | |
| Subcortical grey matter structure volumes | hippocampus (mm3) |
| amygdala (mm3) | |
| thalamus (mm3) | |
| nucleus accumbens (mm3) | |
| caudate nucleus (mm3) | |
| putamen (mm3) | |
| pallidum (mm3) | |
| Hippocampal subfield volumes | CA1 (mm3) |
| CA2/CA3 (mm3) | |
| CA4 (mm3) | |
| Fimbria (mm3) | |
| Subiculum (mm3) | |
| Molecular layer (mm3) | |
| GC-ML-DG (mm3) | |
| HATA (mm3) |