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(a) Distance between the heavy atoms for the H-bonds formed between the tafamidis (AB pocket) carboxylate and V122I Lys-15 residues, (b) Distance between the heavy atoms forming the tafamidis (AB pocket) N and Thr-119(A) hydrogen bonds, (c) Distance between the tafamidis carboxylate oxygens (A’B’ pocket) and V122I Lys-15 residues.
