Table 3.
Comparison of Follow-Up Imaging and Procedures Within 12 Months on the Basis of Initial or Follow-Up LDCT
| Test | LDCT (n = 6,993)a |
|||
|---|---|---|---|---|
| Initial LDCT (n = 5,971)b |
Follow-Up LDCT (n = 1,022)c |
|||
| % With Further Evaluation | Adjusted Rate (95% CI)d | % With Further Evaluation | Adjusted Rate (95% CI)d | |
| Any chest imaging (not including LDCT) | 20.70 (19.67-21.73) | 15.26 (14.06-16.45) | 18.79% (16.39-21.19) | 13.70% (10.85-16.54) |
| Any chest imaging (including LDCT) | 24.77% (23.67-25.87) | 19.13% (17.87-20.38) | 23.78% (21.16-26.39) | 18.10% (15.03-21.17) |
| CT | 20.60% (19.57-21.63) | 15.27% (14.08-16.46) | 18.69% (16.29-21.08) | 13.80% (10.97-16.63) |
| PET/MRI | 0.29% (0.14-0.22) | 0.10% (-0.09 to 0.29) | 0.20% (0-0.47) | 0% (-0.48 to 0.48) |
| Any procedures | 3.94% (3.43-4.44) | 3.32% (2.77-3.86) | 2.94% (1.85-4.02) | 2.25% (1.00-3.50) |
| Bronchoscopy | 2.46% (2.06-2.86) | 2.04% (1.60-2.49) | 1.86% (1.03-2.69) | 1.37% (0.34-2.40) |
| Percutaneous | 1.67% (1.34-2.01) | 1.49% (1.13-1.85) | 0.78% (0.24-1.33) | 0.68% (0.01-1.36) |
| Mediastinoscopy | 0.27% (0.13-0.40) | 0.27% (0.12-0.42) | 0.10% (0-0.29) | 0.10% (-0.19 to 0.39) |
| Thoracoscopy | 1.22% (0.94-1.51) | 1.17% (0.87-1.47) | 0.59% (0.11-1.06) | 0.49% (-0.11 to 1.09) |
| Thoracotomy | 0.54% (0.35-0.73) | 0.50% (0.29-0.71) | 0.20% (0-0.47) | 0.20% (-0.17 to 0.56) |
Data are presented as percent (95% CI). See Table 1 legend for expansion of abbreviation.
a
Patients undergoing LDCT are aged 55 to 80 y, with complete insurance coverage in 18 mo before and 12 mo after LDCT.
b
Initial LDCT: those without chest imaging (chest CT, chest MRI/PET) in 18 mo before the index LDCT in 2016.
c
Follow-up LDCT: those with chest imaging (chest CT, chest MRI/PET) in 18 mo before the index LDCT in 2016.
d
Adjusted rate is the difference between the LDCT cohort and the control cohort.