Table 3.
Working memory evaluated by Morris water maze test along the RJ long-term administration in rats icv injected with STZ or control solution with an intertrial interval of 15 min (Period 3 - ITI 15).
| Parameters | Group |
Trial |
Trial/Group |
|||
|---|---|---|---|---|---|---|
| F 3,616 | P | F 3,616 | P | F 3,616 | P | |
| LAT | 10,865 | <0,001 | 41,663 | <0,001 | 4,378 | <0,001 |
| DIST | 11,178 | <0,001 | 38,468 | <0,001 | 2,724 | 0,008 |
| %T-A_CONT | 8,732 | <0,001 | 40,589 | <0,001 | 4,844 | <0,001 |
| Parameters | Day |
Day/Group |
Day/Trial |
Day/Trial/Group |
||||
|---|---|---|---|---|---|---|---|---|
| F 3,616 | P | F 3,616 | P | F 3,616 | P | F 3,616 | P | |
| LAT | 3,589 | 0,009 | --- | --- | --- | --- | --- | --- |
| DIST | 5,532 | <0,001 | --- | --- | --- | --- | --- | --- |
| %T-A_CONT | 2,801 | 0,029 | --- | --- | 1,989 | 0,025 | --- | --- |
Result of the statistical analysis of behavioral data in the Morris Water Maze employing a three-way Analysis of ANOVA, having groups as the between-subjects factor and session and trial within-subjects factors, followed by Bonferroni post-test. The level of significance considered as significant was set at 5% (P < 0.05).