Figure 4.

Liver function tests after 4‐wk treatments with SARM‐2f or testosterone enanthate (TE) in monkeys. Male cynomolgus monkeys were treated with daily oral SARM‐2 (1, 3, or 10 mg/kg) or intramuscular injections once every 2 wks of TE (2 mg/kg) for 4 wks. Plasma levels of (A) asparagine aminotransferase (AST); (B) alanine aminotransferase (ALT) are shown. Treatment with SARM‐2f or TE did not alter the ALT and AST levels, either. Data represent the mean ± SD(n = 3); The effects of SARM‐2f on ALT and AST levels were analyzed by Dunnett's test, and those of testosterone were analyzed by Student's t test