Figure 2.

Adjusted^a hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) during 2-years follow-up according to type of atrial fibrillation. The reference group is patients with paroxysmal AF. ^aHazard ratios were adjusted for age, gender, race, smoking, diabetes, hypertension, stroke/transient ischaemic attack, history of bleeding, cardiac failure, vascular disease, moderate-to-severe chronic kidney disease, and anticoagulant treatment at baseline. The model for major bleeding was furtherly adjusted for heavy alcohol consumption.