Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 31;11:12. doi: 10.3389/fphys.2020.00012

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Huguenard, Cseresznye, Evans, Oberlin, Langlois, Ferguson, Darcey, Nkiliza, Dretsch, Mullan, Crawford and Abdullah.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Examination of TG, DG, and CE lipids by unsaturation and chain length status in mTBI, PTSD, and mTBI + PTSD diagnostic groups with and without ε4 stratification. (A) There was a main effect of diagnosis for MUFA TG (p = 0.054). (B) There was a main effect of diagnosis in TG chain length 58 (p = 0.026). (C) There was an interaction of diagnosis with ε4 status for MUFA (p = 0.004) and PUFA (p = 0.041). (D) There was an interaction of diagnosis with ε4 status in TG chain lengths: ≤ 48 (p = 0.007), 54–55 (p = 0.011), and 56 (p = 0.014). (E) There was a main effect of diagnosis in SFA (p = 0.001), MUFA (p = 0.011), and PUFA DG (p = 0.03). (F) There was a main effect of diagnosis in DG chain length: ≤ 32 (p = 0.035), 34–36 (p = 0.001), and 38 (p = 0.002). (G) There was an interaction of diagnosis with ε4 status in SFA DG (p = 0.000208). (H) There was an interaction of diagnosis with ε4 status for DG chain length: ≤ 32 (p = 0.000415), 34–36 (p = 0.001), and 38 (p = 0.001). (I) No main effect or interaction effect were found significant for CE unsaturation states. (J) No main effect or interaction effect were found significant for CE chain length. Statistical analyses; MLM with LSD post hoc, p ≤ 0.05 cut-off. ^∗p ≤ 0.05, ^∗∗p ≤ 0.01, ^∗∗∗p ≤ 0.001 vs. control (A,B and E,F), ε4− and ε4+ respective controls (C,D, G,H, and I,J). TG, Triglycerides; DG, Diglycerides; CE, Cholesterol esters; SFA, saturated fatty acid; MUFA, Mono-unsaturated fatty acid; PUFA, Poly unsaturated fatty acid.