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. 2020 Jan 31;11:12. doi: 10.3389/fphys.2020.00012

FIGURE 4.

FIGURE 4

Investigation of plasma protein biomarkers using immunoassays. (A) No significant changes were observed between diagnostic groups’ FABP3 peripheral levels. (B) No significant differences were observed between diagnostic groups’ GFAP peripheral levels. (C) A main effect of diagnosis was observed for Aβ38 (p = 0.045) but was non-significant in the ANOVA. (D) No significant differences were observed between diagnostic groups’ Aβ40 peripheral levels. (E) No significant differences were observed between diagnostic groups’ Aβ42 peripheral levels. (F) There was a main effect of diagnosis on Aβ42/Aβ40 ratio (p = 0.028). Statistical analyses; GLM for test of main and interaction effects, One Way ANOVA with LSD post hoc for multiple comparison, p ≤ 0.05 cut-off. ∗p ≤ 0.05, ∗∗p ≤ 0.01 vs. control. FABP3, Fatty acid binding protein 3; GFAP, Glial Fibrillary Acid Protein; Aβ, Amyloid-β.