Figure EV1. Confirmation of the anabolic activity of GTx‐024.

Orchiectomized (ORX) male CD2F1 mice were treated with GTx‐024 (GTx; 15 mg/kg; n = 12) or vehicle (Veh; n = 13) once daily by oral gavage for 28 days. Sham‐orchiectomized (intact) mice (n = 14) were treated identically with vehicle.

• A
  Terminal body weights.
• B
  Terminal gastrocnemius weights.
• C
  Terminal quadriceps weights.
• D
  Forelimb grip strength expressed as % baseline defined as (end of study grip strength) × 100/(pre‐treatment grip strength).

Data information: P‐values are provided in Appendix Table S9. One‐way ANOVA followed by Tukey's multiple comparisons procedure. Data are presented as means ± SD.