Table 1.
Clinical profile of study participants (females: healthy subjects and TNBC patients) from London Health Science Center, London, Ontario, Canada.
| Characteristics | Number (range) | KP (pmol/L) (mean ± SEM) |
|---|---|---|
| Normal subjects age (years) (n = 26) | Mean 34 (20–52) | 39.1 ± 2.3 |
| Early disease (nonmetastatic) TNBC age (years) (n = 25) | Mean 54.8 (27–79) | 78 ± 6.9 |
| Tumor size (mm) | Mean 25.3 (4–55) | |
| Blood collection | ||
| Before any treatment | 18 | 77.83 ± 5.5 |
| Before any surgery | 21 | 82.55 ± 6.1 |
| During/after chemotherapy | 3 | 96.6 ± 7.1 |
| After tumor removing surgery | 4 | 68.3 ± 6.7 |
| After radiation therapy | 0 | |
| Tumor size | ||
| T1 | 13 | |
| T2 | 7 | |
| T3 | 1 | |
| T4 | 4 | |
| Node status | ||
| N0 | 16 | |
| N1 | 5 | |
| N2 | 2 | |
| N3 | 1 | |
| Nx | 1 | |
| Metastatic disease TNBC age (years) (n = 27) | Mean 62.1 (40–85) | 64.9 ± 6.8 |
| No surgery (primary tumor present) | 8 | 66.0 ± 5.5 |
| Surgery (tumor removed) | 19 | 64.4 ± 6.1 |
| No chemotherapy | 12 | 77.8 ± 5.4 |
| Chemotherapy | 13 | 62.1 ± 7.1 |
| Radiation therapy | 12 | 73.9 ± 6.6 |
| Site of metastasis | ||
| Brain | 5 | |
| Lung/pleura | 12 | |
| Bone | 7 | |
| Lymph nodes/lymphatics | 10 | |