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. 2020 Feb 7;10:2105. doi: 10.1038/s41598-019-56024-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Protein-Protein Interaction (PPI) analysis of the identified proteins from comparative proteomic analysis of OGS using IPA and String networks. (A) PPI illustration of tight interaction of altered proteins. (B) PPI network showing all the proteins are tightly networked at highest confidence of 0.900 at STRING network analysis.