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. 2020 Feb 7;10:2079. doi: 10.1038/s41598-019-55660-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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LWPH based classification of three DNA types, i.e., A-DNA, B-DNA, and Z-DNA. The average persistent Betti number (aPBN) from our LWPH for three types of DNAs. We discretize the aPBN equally into a series of numbers and use these values as features for PCA. It can be seen that LWPH based aPBN and PCA results can clearly discriminate the three DNA types.