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. 2020 Feb 7;10:2141. doi: 10.1038/s41598-020-59082-4

Figure 7.

Figure 7

Estimation of the half-maximum effective concentration of α-GD2 TMs. UniCAR 28/ζ NK-92 cells were incubated with GD2-expressing JF Luc cells at an effector to target (E:T) ratio of 5:1. The α-GD2 scFv or α-GD2 IgG4 TMs were added at the indicated concentrations. After 4 hrs of co-culture, target cell lysis was determined using a luminescence-based assay. Results are shown as mean ± SD of data from two independent experiments.