Table 1.
Patients’ characteristics.
| Variable | Level | N (%) | ODG (n = 45, %) | DA, IDH-m (n = 80, %) | DA, IDH-w (n = 28, %) | p value |
|---|---|---|---|---|---|---|
| Age | <40 yr | 66 (43) | 16 (36) | 44 (55) | 6 (21) | 0.004 |
| ≥40 yr | 87 (57) | 29 (64) | 36 (45) | 22 (79) | ||
| Sex | M | 86 (56) | 23 (51) | 49 (61) | 14 (50) | 0.419 |
| F | 67 (44) | 22 (49) | 31 (39) | 14 (50) | ||
| Tumor size | <6 cm | 108 (71) | 31 (69) | 58 (73) | 19 (68) | 0.856 |
| ≥6 cm | 42 (27) | 14 (31) | 21 (26) | 7 (25) | ||
| Tumor location | Frontal lobe | 82 (54) | 30 (67) | 45 (56) | 7 (25) | 0.001 |
| Non-frontal lobe | 71 (46) | 15 (33) | 35 (44) | 21 (75) | ||
| EOR | GTR | 71 (46) | 24 (53) | 38 (48) | 9 (32) | 0.202 |
| Non-GTR | 82 (54) | 21 (47) | 42 (52) | 19 (68) | ||
| RT | Yes | 102 (67) | 26 (58) | 56 (70) | 20 (71) | 0.318 |
| No | 51 (33) | 19 (42) | 24 (30) | 8 (29) | ||
| CTx | Yes | 38 (25) | 15 (33) | 18 (23) | 5 (18) | 0.258 |
| No | 115 (75) | 30 (67) | 62 (77) | 23 (82) | ||
| RT + CTx | Yes | 26 (17) | 8 (18) | 14 (17) | 4 (14) | 0.914 |
| No | 127 (83) | 37 (82) | 66 (83) | 24 (86) | ||
| MGMT | Methylation | 111 (73) | 40 (89) | 63 (79) | 8 (29) | 0.869 |
| Unmethylation | 40 (26) | 5 (11) | 17 (21) | 18 (64) |
Abbreviations: ODG, oligodendroglioma; DA, diffuse astrocytoma; EOR, extent of resection; GTR, gross total resection; RT, radiotherapy; CTx, chemotherapy; Tx, treatment; MGMT, O6-methylguanine-DNA methyltransferase promotor.