Appendix Table 1:
Disposition of fullerene C60 in selected tissues in male F344 rats following IV administration of 5 mg/kg b.wt.a
Fullerene C60 Concentration (μg/g) | |||
---|---|---|---|
Matrix | Time (h) | ||
Mean | SDb | ||
0.5 | 79 | 8 | |
2 | 68 | 15 | |
Lung | 6 | 50 | 9 |
24 | 31 | 3 | |
168 | 19 | 2 | |
0.5 | 38 | 13 | |
2 | 76 | 18 | |
Spleen | 6 | 80 | 27 |
24 | 93 | 7 | |
168 | 57 | 30 | |
0.5 | 85 | 26 | |
2 | 100 | 23 | |
Liver | 6 | 96 | 92 |
24 | 92 | 17 | |
168 | 97 | 45 | |
0.5 | 22 | 3 | |
2 | 28 | 3 | |
Kidney | 6 | 25 | 10 |
24 | 17 | 10 | |
168 | 0.25 | 0.3 |
Additional tissues and excreta were examined but were below the limit of quantification (1-5 μg/g)
SD = standard deviation