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. 2020 Feb 7;10:2066. doi: 10.1038/s41598-020-59031-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of EGFR mutation status on prognostic value of CEA^In in patients with advanced stage lung adenocarcinoma. (A) Adjusted progression-free survival (PFS) was derived from multivariable Cox model to assess the correlation between CEA^In expression and PFS in all lung adinocarcinoma patients (top left), EGFR wild-type patients (middle left), and EGFR mutants (bottom left). (B) Adjusted overall survival (OS) derived from multivariable Cox model to assess correlation between CEA^In expression and OS in all lung adenocarcinoma patients (top right), EGFR wild-type patients (middle right), and EGFR mutants (bottom right). Variables included in the model were age, sex, stage, smoking and CEA^In expression. The statistical significance was set at P < 0.0071.