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. 2020 Feb 7;10:2114. doi: 10.1038/s41598-020-58845-3

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© The Author(s) 2020

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3D protein structure. The arginine (blue) in α1 is mutated into a Tryptophan (red). Due to this mutation, the hydrogen bonds (yellow dotted lines) between arginine and glutamine in α3 (green) are lost.