Table 3.

Cases with reinstatement of TRT.

Case	TFT at start of TRT	Antibodies	Time from starting lithium to initiating TRT	Time from discontinuing lithium to stopping TRT	Time from stopping TRT to reinstating TRT	TFT at or near time of TRT reinstatement	Reason for TRT reinstatement as recorded in the medical notes
1	Subclinical	N/A	4.3 months	2 days	11 days	Overt	Increasing TSH and decreasing fT4
2	Subclinical	N/A	3.2 months	0 days	16 days	Normal	Reinstated via primary care, no comment in journal
3	Subclinical	N/A	5.3 months	1.9 years	1.2 years	TSH and fT4 not taken	Reinstated via primary care, no comment in journal
4	Overt	N/A	2.3 months	0 days	1.6 years	Low fT4 only	Reinstated via psychiatry clinic, low fT4
5	Subclinical	TPO negative	4.5 years	2.5 years	3.4 years	Subclinical	Reinstated via primary care, no comment in journal
6	Overt	N/A	9.7 months	10 days	4.5 years	TSH 7.5 IU/mL fT4 not taken	Postpartum

N/A: not available; TFT: thyroid function tests; TRT: thyroid replacement therapy; TPO: thyroid peroxidase antibodies; fT4: free serum thyroxine; TSH: thyroid stimulating hormone.