. 2019 Jul-Sep;31(3):368–378. doi: 10.5935/0103-507X.20190060

Table 2.

Studies evaluating N-terminal pro-B-type natriuretic peptide and mortality

Study	N	Septic shock %	Timing of NT-proBNP	Definition of LV dysfunction	Mortality (%)		Optimal cut-off (pg/mL)	AUC
Study	N	Septic shock %	Timing of NT-proBNP	Definition of LV dysfunction	ICU/hospital	30-day	Optimal cut-off (pg/mL)	AUC
Mokart et al.⁽⁴²⁾	51	100	Day 2	LVEF < 55%	51	---	6,624	0.87
Varpula et al.⁽⁷⁸⁾	254	---	Hospital admission	High PCWP quartiles	13/26	---	7,090	0.631
Sturgess et al.⁽⁸²⁾	21	100		LV stroke work index	2	---	400	0.67
Brueckmann et al.⁽⁸³⁾	57	0	Day 2	LVEF 35 - 50% - Moderate	---	28	1400	0.68
Roch et al.⁽⁸⁴⁾	39	100	Day 2	LVEF < 35% - Severe	56	---	13,600	0.8
Guaricci et al.⁽⁸⁵⁾	40	0	Day 3	LVEF < 45%	---	55	1,000	0.99

NT-proBNP - N-terminal pro-B-type natriuretic peptide; LV - left ventricle; ICU - intensive care unit; AUC - area under the curve; LVEF - left ventricular ejection fraction; PCWP - Pulmonary capillary wedge pressure.