. 2019 Jul-Sep;31(3):379–385. doi: 10.5935/0103-507X.20190061

Table 2.

Main results

Author, Country	Main results
Rahman et al.⁽⁷⁾ Canada	Mortality at 28 days was multiplied by 1.4 for every point increase of the NUTRIC score. There is a strong positive association between nutritional adequacy and 28-day survival in patients with a high NUTRIC score, but this association decreases with the decreasing NUTRIC score. Higher NUTRIC scores are also significantly associated with higher 6-month mortality (p < 0.001).
Moretti et al.⁽⁹⁾ Argentine	Mortality increased in relation to the score (p < 0.001). The mean CRP was higher in mortality (p = 0.001) and VM time (p = 0.010), and the AUC increased in a similar way to IL-6 in the original work (0.008 and 0.007, respectively).
Lee et al.⁽¹⁰⁾ Malaysia	For patients with low nutritional risk, mortality was increased by approximately 6 times in the group that received ≥ 2/3 of prescribed than both < 2/3 (p = 0.032).
Mendes et al.⁽¹¹⁾ Portugal	A high NUTRIC score was associated with longer hospitalization (p < 0.001), fewer days free of MV (p = 0.002) and higher 28-day mortality (p < 0.001).
Mukhopadhyay et al.⁽¹²⁾ Singapore	The NUTRIC score (p < 0.001) was associated with 28-day mortality.
Rosa et al.⁽¹³⁾ 2016 Brazil	The Portuguese version was easily introduced into four Brazilian ICUs, and the prevalence of patients with a high score was 46%.
Kalaiselvan et al.⁽¹⁴⁾ Indian	NUTRIC score (p < 0.001), use of vasopressor drug (p < 0.005) and BMI (p < 0.002) were associated with 28-day mortality. In 273 patients who received MV, significant differences were noted between the high and low NUTRIC groups in terms of mortality (p < 0.001), ICU LOS (p < 0.014), and duration of MV (p < 0.001).
Coltman et al.⁽¹⁵⁾ United States	Patients determined to be at nutritional risk using the NUTRIC score alone or in combination with any other tool had the highest rates of death. A larger proportion of patients requiring additional rehabilitation after discharge was seen with NUTRIC score. Patients identified as being at nutritional risk or malnourished using NUTRIC had the longest hospital LOS and ICU LOS.
Özbilgin et al.⁽¹⁶⁾ Turkey	There was a positive correlation with mortality and the NUTRIC score (p=0.020) and pulmonary complications (p = 0.030).
de Vries et al.⁽¹⁷⁾ The Netherlands	The discriminative ability of the NUTRIC score for 28-day mortality is (ROC-AUC) 0.768 (95% CI 0.722 - 0.814) with an associated LR+ of 1.73 (95% CI 1.53 - 1.95) and LR− of 0.24 (95% CI 0.14 - 0.39) when comparing low with high (> 4) scores.
Lew et al.⁽¹⁸⁾ Singapore	High NUTRIC score was associated with hospital mortality (p < 0.001).
Compher et al.⁽¹⁹⁾ Canada	In high-risk but not low-risk patients, mortality was lower with greater protein (4-d sample: p = 0.003; 12-d sample: p = 0.003) and energy (4-d sample: p < 0.001; 12-d sample: p < 0.001) intake. In high-risk but not low-risk patients, time to discharge alive was shorter with greater protein (4-d sample: p = 0.010; 12-d sample: p = 0.002) and energy intake (4-d sample: p = 0.020; 12-d sample: p = 0.002).

NUTRIC - Nutrition Risk in the Critically Ill; CRP - C-reactive protein; MV - mechanical ventilation; AUC - area under the curve; IL - interleukin; ICU - intensive care unit; BMI - body mass index; LOS - length of stay; ROC - receiver operating characteristic; LR - likelihood; d - day; 95%CI - 95% confidence interval.