Table 1.
Non–screen detecteda |
Screen detecteda |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Overall | Rectum | Colon | p value | Rectum | Colon | p value | ||||||
Number of patients | 1055 | 693 | 220 | 54 | 11 | |||||||
Median age (IQR) | 61 (50–68) | 58 (48–67) | 64 (54–74) | <0.001 | 65.5 (63–69) | 67 (61–74) | 0.92 | |||||
n
|
% |
n
|
% |
n
|
% |
n
|
% |
n
|
% |
|
||
Sex | ||||||||||||
Male | 501 | 47.5% | 327 | 47.2% | 98 | 44.5% | 0.54 | 35 | 64.8% | 7 | 63.6% | 1 |
Female | 554 | 52.5% | 366 | 52.8% | 122 | 55.5% | 19 | 35.2% | 4 | 36.4% | ||
Grade | ||||||||||||
I | 775 | 73.5% | 516 | 74.5% | 147 | 66.8% | <0.001 | 48 | 88.9% | 9 | 81.8% | 0.66 |
II | 103 | 9.8% | 50 | 7.2% | 39 | 17.7% | 5 | 9.3% | 2 | 18.2% | ||
III | 11 | 1.0% | 3 | 0.4% | 7 | 3.2% | – | – | – | – | ||
I/IIb | 160 | 15.2% | 124 | 17.9% | 24 | 10.9% | – | – | – | – | ||
I/II/IIIc | 6 | 0.6% | 0 | – | 3 | 1.4% | 1 | 1.9% | – | – | ||
Histological diagnosis | ||||||||||||
Endoscopy | 930 | 88.2% | 676 | 97.5% | 144 | 65.5% | <0.001 | 54 | 100.0% | 11 | 100.0% | 1 |
Surgery | 114 | 10.8% | 15 | 2.2% | 69 | 31.4% | – | – | – | – | ||
Autopsy | 7 | 0.7% | 2 | 0.3% | 5 | 2.3% | – | – | – | – | ||
Radiological biopsy | 2 | 0.2% | – | – | 1 | 0.5% | – | – | – | – | ||
Unknown | 2 | 0.2% | – | – | 1 | 0.5% | – | – | – | – | ||
Therapy | ||||||||||||
Endoscopic local excision | 813 | 77.1% | 634 | 91.5% | 78 | 35.5% | <0.001 | 52 | 96.3% | 7 | 63.6% | 0.006 |
TEM | 22 | 2.1% | 21 | 3.0% | – | – | – | – | – | – | ||
Radical resection | 212 | 20.1% | 36 | 5.2% | 137 | 62.3% | 2 | 3.7% | 4 | 36.4% | ||
Unknown/NA | 8 | 0.8% | 2 | 0.3% | 5 | 2.3% | – | – | – | – |
IQR: interquartile range; NA: not available; NET: neuroendocrine tumour; TEM: transanal endoscopic microsurgery.
Excludes 77 patients with a colorectal NET for which the specific primary tumour location was not available.
Carcinoid/Suggestive for Grade I or II.
NET with no data on histological grade.