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. 2020 Jan 31;11:4. doi: 10.3389/fneur.2020.00004

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Copyright © 2020 Welby, Caudill, Yitsege, Hamad, Bunyak, Zohn, Maynard, LaMantia, Mendelowitz and Lever.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Endoscopic evidence of palatal and laryngeal anomalies in LgDel mice. Representative images showing advancement of the endoscope into the pharynx (A,B) and laryngeal inlet (C,D) to visualize the glottis (E,F). Compared to WT mice (A,C,E), LgDel mice displayed several minor structural anomalies, including soft palate asymmetry (red arrowheads), and in this mouse, strands of fur (white arrowheads) were found lodged within the laryngeal inlet (B); narrowed epiglottis with visibly absent aryepiglottic folds (D); and extraneous mucosa (red asterisk) along the medial edge of the arytenoids (F). Black asterisks, arytenoid mucosa; white arrows, aryepiglottic folds; red arrows, vocal folds; yellow arrow, laryngeal pouch. Images were adjusted for color, brightness, and contrast to enhance visualization of key features.