Figure 8.

Inflammation of lung tissue in LgDel mice. Representative image of H&E stained lung tissue from a WT (A) and LgDel (B) mouse taken with the 10X objective; scale bar = 100 microns. The LgDel sample shows evidence of inflammation, including pools of erythrocytes (red staining). (A',B') Processed images showing isolation of pixels with pools of erythrocytes in LgDel but not WT samples. (A”,B”) Magnification of boxed regions in (A,B) showing greater detail of inflammation found in the LgDel lungs. Images were taken with the 20X objective; scale bar = 50 microns. (C) Graph showing significantly increased lung inflammation in LgDel compared to WT littermates. **p < 0.01.