Table 1.
Characteristics of NB patients with high risk
| Characteristics | Total cases, N (%) |
|---|---|
| Age (months) | |
| < 18 | 7 (6.0) |
| ≥ 18 and < 60 | 80 (69.0) |
| ≥ 60 | 29 (25.0) |
| Sex | |
| Female | 56 (48.3) |
| Male | 60 (51.7) |
| Primary site | |
| Abdomen | 93 (80.2) |
| Thorax | 20 (17.2) |
| Other | 3 (2.6) |
| MYCN gene | |
| Amplification | 38 (32.8) |
| Non-amplification | 78 (67.2) |
| NSE (ng/ml) | |
| < 370 | 88 (75.9) |
| ≥ 370 | 28 (24.1) |
| LDH (IU/L) | |
| ≤ 500 | 14 (12.1) |
| > 500 and < 1500 | 88 (75.9) |
| ≥ 1500 | 14 (12.1) |
| Metastatic site | |
| Bone | 84 (72.4) |
| Bone marrow | 72 (62.1) |
| Distant lymph node | 76 (65.5) |
| Liver | 20 (17.2) |
| Central nervous system | 20 (17.2) |
| Number of organs with metastasis | |
| < 3 | 59 (50.9) |
| 3 | 39 (33.6) |
| > 3 | 18 (15.5) |