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Histogram of the distribution of pCADD score for (pre-)miRNA transcripts and their surrounding up- and downstream regions. Vertical lines indicate the mean values of each distribution with a mean of 9.987 for miRNA and 7.205 for Up&Down. The one-tailed Mann–Whitney U-test between both distributions provided a p-value of 0.0 and a ROC-AUC of 0.613 in favour of miRNA over the Up&Down stream regions
