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. 2020 Feb 7;21:29. doi: 10.1186/s13059-020-1946-2

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6. — Innate immune system pathways showing Native American ancestry enrichment. Illustration of three interconnected pathways from the innate immune system—the RIG-I-like receptor signaling pathway, the Toll-like receptor signaling pathway, and the cytosolic DNA-sensing pathway—highlighting genes (proteins) that show Native American ancestry enrichment