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A CRISPR-Cas9 knockout screen identified genes required for the cytotoxicity anti-cancer drugs. a The panel of 27 screened drugs are classified based on their therapeutic targets and mechanisms of action. b Drugs are grouped according to their primary target/effector pathways and cellular functions. A single drug may be included in multiple categories. c Schematic design of pooled CRISPR library screens to identify the genes involved in drug sensitivity
