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. Author manuscript; available in PMC: 2020 Feb 7.
Published in final edited form as: Aliment Pharmacol Ther. 2014 Apr 20;39(12):1349–1362. doi: 10.1111/apt.12749

Table 3.

Total number of subjects required for comparative efficacy RCTs between anti-TNF agents for CD induction and maintenance of remission

Total subject number (induction/maintenance) Infliximab Certolizumab pegol Adalimumab
Infliximab 3272/558 4780/3076
Certolizumab pegol 3272/558 104518/286
Adalimumab 4780/3076 104518/286