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. 2020 Feb 7;18:31. doi: 10.1186/s12957-020-1809-z

Table 2.

Diagnostic performance

AUC 95% CI Sensitivity Specificity PPV NPV Accuracy
MUC5AC
 PC vs. controls 0.825 0.760–0.890 0.541 0.951 0.846 0.807 0.815
 EPC vs. controls 0.793 0.695–0.890 0.500 0.951 0.714 0.886 0.863
 LPC vs. controls 0.856 0.783–0.930 0.581 0.951 0.75 0.900 0.877
CA19-9
 PC vs. controls 0.836 0.770–0.902 0.820 0.618 0.515 0.874 0.685
 EPC vs. controls 0.844 0.752–0.937 0.833 0.618 0.347 0.938 0.660
 LPC vs. controls 0.827 0.740–0.914 0.806 0.618 0.347 0.927 0.656
Combination
 PC vs. controls 0.894 0.844–0.943 0.738 0.886 0.763 0.872 0.837
 EPC vs. controls 0.892 0.819–0.966 0.767 0.886 0.622 0.940 0.863
 LPC vs. controls 0.895 0.837–0.954 0.710 0.886 0.611 0.924 0.851

AUC area under receiver operating characteristic curve, EPC early-stage pancreatic cancer, LPC late-stage pancreatic cancer, NPV negative predictive value, PC pancreatic cancer, PPV positive predictive value