Table 4.
Adjusted mean values of urine chemistries by antibiotic use
| No antibiotic use | Duration of Antibiotic Use | ||
|---|---|---|---|
| <2 months | >=2 months | ||
| 40 to 49/59 years | |||
| Nurses’ Health Study I | |||
| - Calcium (mg/d) | 197 | 187 | 178 |
| - Oxalate (mg/d) | 28 | 29 | 29 |
| - Citrate (mg/d) | 642 | 627 | 609 |
| - Volume (L/d) | 1.7 | 1.8 | 1.8 |
| - pH | 6.05 | 6.03 | 5.91* |
| Nurses’ Health Study II | |||
| - Calcium (mg/d) | 205 | 205 | 193 |
| - Oxalate (mg/d) | 30 | 30 | 30 |
| - Citrate (mg/d) | 816 | 782* | 754* |
| - Volume (L/d) | 2.0 | 2.0 | 2.0 |
| - pH | 6.17 | 6.14 | 6.15 |
| 20 to 39 years | |||
| Nurses’ Health Study I | |||
| - Calcium (mg/d) | 185 | 189 | 174 |
| - Oxalate (mg/d) | 29 | 29 | 30 |
| - Citrate (mg/d) | 629 | 629 | 624 |
| - Volume (L/d) | 1.7 | 1.8 | 1.8 |
| - pH | 6.09 | 6.02 | 5.95* |
| Nurses’ Health Study II | |||
| - Calcium (mg/d) | 201 | 205 | 199 |
| - Oxalate (mg/d) | 30 | 30 | 30 |
| - Citrate (mg/d) | 819 | 783 | 778 |
| - Volume (L/d) | 1.9 | 2.0 | 2.0 |
| - pH | 6.18 | 6.15 | 6.16 |
Values adjusted for age, kidney stone status, BMI, use of alcohol, dietary intake of oxalate, calcium, magnesium, potassium, animal protein, total fluid, supplemental use of calcium, urinary creatinine and sodium
*
p<0.05