Fig. 6. (A) Living cell CHA-HCR-DNAzyme imaging of miR-21 in (a) MCF-7 cells or (b) anti-miR-21 antisense inhibitor-pretreated MCF-7 cells. (c) The H4-excluded CHA-HCR-DNAzyme imaging of MCF-7 cells was executed as an important control. Scale bar: 20 μm. (B) The fluorescence enhancement of these different miR-21-sensing platforms. Columns a, b, and c correspond to the confocal images a, b and c of (A), respectively. These results are expressed as mean ± SD (standard deviation, n = 5) (***P < 0.001).
