Source	Search strategy	Hits retrieved
ALOIS (www.medicine.ox.ac.uk/alois) [Date of most recent search: 16 Oct 2019]	hip OR fracture OR surgery OR operation OR femur OR femoral	June 2014: 120 June 2018: 3 Oct 2019: 126
Cochrane Bone, Muscle and Trauma Group Specialised Register [Date of most recent search: 16 Oct 2019]	hip OR fracture OR surgery OR operation OR femur OR femoral	June 2018: 220 (all dates) Oct 2019: 127
MEDLINE In‐process and other non‐indexed citations and MEDLINE 1950‐present (Ovid SP) [Date of most recent search: 16 Oct 2019] [Note: for the June 2018 top‐up search, a new term was added and searched across all dates: geriatric* assess*. This term identified 994 results from Medline]	1. exp Dementia/ 2. Delirium/ 3. Wernicke Encephalopathy/ 4. Delirium, Dementia, Amnestic, Cognitive Disorders/ 5. dement*.mp. 6. alzheimer*.mp. 7. (lewy* adj2 bod*).mp. 8. deliri*.mp. 9. (chronic adj2 cerebrovascular).mp. 10. ("organic brain disease" or "organic brain syndrome").mp. 11. ("normal pressure hydrocephalus" and "shunt*").mp. 12. "benign senescent forgetfulness".mp. 13. (cerebr* adj2 deteriorat*).mp. 14. (cerebral* adj2 insufficient*).mp. 15. (pick* adj2 disease).mp. 16. (creutzfeldt or jcd or cjd).mp. 17. huntington*.mp. 18. binswanger*.mp. 19. korsako*.mp. 20. or/1‐19 21. exp Femur/ 22. exp Fractures, Bone/ 23. exp Fracture Fixation/ 24. exp Fracture Healing/ 25. or/22‐24 26. 21 and 25 27. (hip or hips or pertrochant* or intertrochant* or trochanteric or subtrochanteric or extracapsular*).ti,ab. 28. ((femur* or femoral*) adj3 (neck or proximal)).ti,ab. 29. 27 or 28 30. ((hip or hips or pertrochant* or intertrochant* or trochanteric or subtrochanteric or extracapsular* or ((femur* or femoral*) adj3 (neck or proximal))) adj4 fracture).ti,ab. 31. geriatric* assess*.ti,ab. 32. randomized controlled trial.pt. 33. controlled clinical trial.pt. 34. randomi?ed.ab. 35. randomly.ab. 36. placebo.ab. 37. drug therapy.fs. 38. trial.ab. 39. groups.ab. 40. ("double‐blind*" or "single‐blind*").ti,ab. 41. (RCT or CCT).ti,ab. 42. or/32‐41 43. (animals not (humans and animals)).sh. 44. 41 not 42 45. 29 or 30 46. 20 and 44 and 45	June 2014: 255 June 2018: 1145 Oct 2019: 123
EMBASE 1980‐2018 June 25 (Ovid SP) [Date of most recent search: 16 Oct 2019] [Note: for the June 2018 top‐up search, a new term was added and searched across all dates: geriatric* assess*. This term identified 674 results from Embase]	1. exp dementia/ 2. Lewy body/ 3. delirium/ 4. Wernicke encephalopathy/ 5. cognitive defect/ 6. dement*.mp. 7. alzheimer*.mp. 8. (lewy* adj2 bod*).mp. 9. deliri*.mp. 10. (chronic adj2 cerebrovascular).mp. 11. ("organic brain disease" or "organic brain syndrome").mp. 12. "supranuclear palsy".mp. 13. ("normal pressure hydrocephalus" and "shunt*").mp. 14. "benign senescent forgetfulness".mp. 15. (cerebr* adj2 deteriorat*).mp. 16. (cerebral* adj2 insufficient*).mp. 17. (pick* adj2 disease).mp. 18. (creutzfeldt or jcd or cjd).mp. 19. huntington*.mp. 20. binswanger*.mp. 21. korsako*.mp. 22. CADASIL.mp. 23. or/1‐22 24. femur/ or femur fracture/ 25. fracture/ 26. 24 and 25 27. (hip or hips or pertrochant* or intertrochant* or trochanteric or subtrochanteric or extracapsular*).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword] 28. fracture*.ti,ab. 29. femur.ti,ab. 30. geriatric* assess*.ti,ab. 31. or/24‐29 32. 23 and 31 33. randomized controlled trial/ 34. trial.ab. 35. randomly.ab. 36. groups.ab. 37. randomi?ed.ti,ab. 38. placebo.ab. 39. RCT.ti,ab. 40. "double‐blind*".ti,ab. 41. or/33‐40 42. 32 and 41	June 2014: 716 June 2018: 1029 Oct 2019: 426
PsycINFO 1806‐June week 3 2018 (Ovid SP) [Date of most recent search: 16 Oct 2019] [Note: for the June 2018 top‐up search, a new term was added and searched across all dates: geriatric* assess*. This term identified 32 results from PsycINFO]	1. exp Dementia/ 2. exp Delirium/ 3. exp Huntingtons Disease/ 4. exp Kluver Bucy Syndrome/ 5. exp Wernickes Syndrome/ 6. exp Cognitive Impairment/ 7. dement*.mp. 8. alzheimer*.mp. 9. (lewy* adj2 bod*).mp. 10. deliri*.mp. 11. (chronic adj2 cerebrovascular).mp. 12. ("organic brain disease" or "organic brain syndrome").mp. 13. "supranuclear palsy".mp. 14. ("normal pressure hydrocephalus" and "shunt*").mp. 15. "benign senescent forgetfulness".mp. 16. (cerebr* adj2 deteriorat*).mp. 17. (cerebral* adj2 insufficient*).mp. 18. (pick* adj2 disease).mp. 19. (creutzfeldt or jcd or cjd).mp. 20. huntington*.mp. 21. binswanger*.mp. 22. korsako*.mp. 23. ("parkinson* disease dementia" or PDD or "parkinson* dementia").mp. 24. or/1‐23 25. (hip or hips or pertrochant* or intertrochant* or trochanteric or subtrochanteric or extracapsular*).ti,ab. 26. fracture*.ti,ab. 27. femur.ti,ab. 28. femoral*.ti,ab. 29. geriatric* assess*.ti,ab. 30. or/25‐28 31. 24 and 30 32. exp Clinical Trials/ 33. randomly.ab. 34. randomi?ed.ti,ab. 35. RCT.ti,ab. 36. groups.ab. 37. placebo.ab. 38. "double‐blind*".ti,ab. 39. or/32‐38 40. 31 and 39	June 2014: 86 June 2018: 203 Oct 2019: 15
CINAHL (EBSCOhost) [Date of most recent search: 16 Oct 2019]	S1 (MH "Dementia+") S2 (MH "Delirium") or (MH "Delirium, Dementia, Amnestic, Cognitive Disorders") S3 (MH "Wernicke's Encephalopathy") S4 TX dement* S5 TX alzheimer* S6 TX lewy* N2 bod* S7 TX deliri* S8 TX chronic N2 cerebrovascular S9 TX "organic brain disease" or "organic brain syndrome" S10 TX "normal pressure hydrocephalus" and "shunt*" S11 TX "benign senescent forgetfulness" S12 TX cerebr* N2 deteriorat* S13 TX cerebral* N2 insufficient* S14 TX pick* N2 disease S15 TX creutzfeldt or jcd or cjd S16 TX huntington* S17 TX binswanger* S18 TX korsako* S19 S1 or S2 or S3 or S4 or S5 or S6 or S7 or S8 or S9 or S10 or S11 or S12 or S13 or S14 or S15 or S16 or S17 or S18 S20 TX hip OR hips OR fracture* OR femur OR femoral OR pertrochant* or intertrochant* or trochanteric or subtrochanteric or extracapsular* S21 (MH "Hip Fractures") S22 S20 OR S21 S23 S19 AND S22 S24 (MH "Randomized Controlled Trials") OR (MH "Clinical Trials") S25 TX randomly S26 AB trial S27 AB placebo S28 AB placebo S29 AB "double‐blind*" S30 AB groups S31 AB groups S32 S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 S33 S23 AND S32	June 2014: 125 June 2018: 107 Oct 2019: 95
ISI Web of Science (1945‐present) and conference proceedings [Date of most recent search: 16 Oct 2019]	Topic=(dement* OR alzheimer* OR "lewy bod*" OR DLB OR "vascular cognitive impairment*" OR FTD OF FTLD OR "cerebrovascular insufficienc*") AND Topic=(hip OR hips OR fracture* OR femur OR femoral OR pertrochant* or intertrochant* or trochanteric or subtrochanteric or extracapsular*) AND Topic=(randomly OR trial OR cluster* OR RCT OR placebo OR randomised OR randomized) Timespan=All years. Databases=SCI‐EXPANDED, SSCI, A&HCI, CPCI‐S, CPCI‐SSH, BKCI‐S, BKCI‐SSH, CCR‐EXPANDED, IC.	June 2014: 324 June 2018: 217 Oct 2019: 76
LILACS (BIREME) [Date of most recent search: 16 Oct 2019]	cadera OR hip OR hips OR caderas OR fractura OR fracture OR fémur OR femur OR fêmur OR quadril [Words] and dementia OR demência OR alzheimer OR "cognitive impair$" OR "deterioro cognitivo" [Words]	June 2014: 12 June 2018: 22 Oct 2019: 1
CENTRAL (The Cochrane Library) (Issue 6 of 12, 2018) [Date of most recent search: 16 Oct 2019]	#1 MeSH descriptor: [Dementia] explode all trees #2 dement* #3 alzheimer* #4 lewy* near/2 bod* #5 deliri* #6 chronic near/2 cerebrovascular #7 "organic brain disease" or "organic brain syndrome" #8 "normal pressure hydrocephalus" and "shunt*" #9 "benign senescent forgetfulness" #10 cerebr* near/2 deteriorat* #11 cerebral* near/2 insufficient* #12 pick* near/2 disease #13 creutzfeldt or jcd or cjd #14 huntington* #15 binswanger* #16 korsako* #17 "cognit* impair*" #18 MeSH descriptor: [Cognition Disorders] explode all trees #19 MCI #20 ACMI #21 ARCD #22 SMC #23 CIND #24 BSF #25 AAMI #26 LCD #27 AACD #28 MNCD #29 MCD #30 "N‐MCI" or "A‐MCI" or "M‐MCI" #31 (cognit* or memory or cerebr* or mental*) near/3 (declin* or impair* or los* or deteriorat* or degenerat* or complain* or disturb* or disorder*) #32 "preclinical AD" #33 "pre‐clinical AD" #34 aMCI or MCIa #35 "CDR 0.5" or "clinical dementia rating scale 0.5" #36 "GDS 3" or "stage 3 GDS" #37 "global deterioration scale" and "stage 3" #38 "mild neurocognit* disorder*" #39 prodrom* near/2 dement* #40 episodic* near/2 memory #41 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 #42 hip or hips or pertrochant* or intertrochant* or trochanteric or subtrochanteric or extracapsular* #43 (femur* or femoral*) near/3 (neck or proximal) #44 MeSH descriptor: [Femur] explode all trees #45 MeSH descriptor: [Fractures, Bone] explode all trees #46 MeSH descriptor: [Fracture Fixation] explode all trees #47 MeSH descriptor: [Fracture Healing] explode all trees #48 #42 or #43 or #44 or #45 or #46 or #47 #49 #48 and #41 in Trials	June 2014: 148 June 2018: 316 Oct 2019: 289
Clinicaltrials.gov (www.clinicaltrials.gov) [Date of most recent search: 16 Oct 2019]	hip OR hips OR surgery OR pertrochant* OR intertrochant* OR trochanteric OR subtrochanteric OR extracapsular OR femur OR femoral | Interventional Studies | dementia OR alzheimer OR alzheimers OR lewy OR vascular cognitive impairment	June 2014: 104 June 2018: 2 Oct 2019: 17
ICTRP Search Portal (http://apps.who.int/trialsearch) [includes: Australian New Zealand Clinical Trials Registry; ClinicalTrilas.gov; ISRCTN; Chinese Clinical Trial Registry; Clinical Trials Registry – India; Clinical Research Information Service – Republic of Korea; German Clinical Trials Register; Iranian Registry of Clinical Trials; Japan Primary Registries Network; Pan African Clinical Trial Registry; Sri Lanka Clinical Trials Registry; The Netherlands National Trial Register] [Date of most recent search: 16 Oct 2019]	#1 hip AND dementia = 5 #2 fracture AND dementia = 9 #3 femur AND dementia = 10	June 2014: 24 June 2018: 40 Oct 2019: 10
TOTAL before de‐duplication		June 2014: 1914 June 2018: 3292 Oct 2019: 1305 TOTAL: 6511
TOTAL after de‐duplication and first‐assessment (Note: first assessment not performed for the Oct 2019)		June 2014: 296 June 2018: 581 Oct 2019: 1079 TOTAL: 1956