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. 2020 Feb 3;13:1027–1035. doi: 10.2147/OTT.S226951

Figure 3.

Figure 3

Effect of foretinib on carcinogenesis-related genes in GC cells. (A) c-MET and CD44 gene expression in gastric cancer cells and (B) mRNA levels of c-MET, HIF-1a, VEGFA, CD44, CD44s, CD44v9, CCND1, COX-2, and ECAD in MKN45, SNU620, MKN28, and AGS cells were determined by quantitative reverse-transcription polymerase chain reaction (qRT-PCR) analysis after treatment with 30 nM foretinib for 48 h. Data are means ± S.D. *P < 0.05; **P < 0.01; ***P < 0.001 (one-way analysis of variance [ANOVA]).