Table 2. Unadjusted primary and secondary outcomes after 2 years’ follow-up.
Repeated PSA test | Control (n = 4,242) | Intervention (n = 3,558) | ORa (95% CI, sign) | Intervention | ||||
---|---|---|---|---|---|---|---|---|
No genetic test (n = 2,323) | Normal genetic risk (n = 1,047) | High genetic risk (n = 136) | ORb (95% CI) | ORc (95% CI) | ||||
All men with a PSA test, N (%) | 1,628 (38.4%) | 1,218 (34.2%) | 0.95 (95% CI 0.78–1.14) | 833 (37.5%) | 261 (24.9%) | 102 (75.0%) | 0.65 (95% CI 0.5–0.78) | 5.96 (95% CI 3.96–8.97) |
Men with an elevated PSA test, N (%) | 97 (2.3%) | 78 (2.2%) | 1.01 (95% CI 0.71–1.43) | 50 (2.2%) | 16 (1.5%) | 9 (6.6%) | 0.71 (95% CI 0.40–1.26) | 3.31 (95% CI 1.57–6.97) |
aControl versus intervention.
bAverage risk versus no genetic test.
cHigh risk versus no genetic test.
Abbreviations: OR, odds ratio; PSA, prostate-specific antigen