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. 2020 Feb 7;17(2):e1003033. doi: 10.1371/journal.pmed.1003033

Table 2. Unadjusted primary and secondary outcomes after 2 years’ follow-up.

Repeated PSA test Control (n = 4,242) Intervention (n = 3,558) ORa (95% CI, sign) Intervention
No genetic test (n = 2,323) Normal genetic risk (n = 1,047) High genetic risk (n = 136) ORb (95% CI) ORc (95% CI)
All men with a PSA test, N (%) 1,628 (38.4%) 1,218 (34.2%) 0.95 (95% CI 0.78–1.14) 833 (37.5%) 261 (24.9%) 102 (75.0%) 0.65 (95% CI 0.5–0.78) 5.96 (95% CI 3.96–8.97)
Men with an elevated PSA test, N (%) 97 (2.3%) 78 (2.2%) 1.01 (95% CI 0.71–1.43) 50 (2.2%) 16 (1.5%) 9 (6.6%) 0.71 (95% CI 0.40–1.26) 3.31 (95% CI 1.57–6.97)

aControl versus intervention.

bAverage risk versus no genetic test.

cHigh risk versus no genetic test.

Abbreviations: OR, odds ratio; PSA, prostate-specific antigen